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A Review on: “Recent Updates on Poly-Adp-Ribosylation (Parylation) in Physiology and Pathology”


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Authors : Pritam Paramguru Mahapatra, Manaswini Giri

Volume/Issue : Volume 5 - 2020, Issue 5 - May

Google Scholar : http://bitly.ws/9nMw

Scribd : https://bit.ly/36L01zH

DOI : 10.38124/IJISRT20MAY326

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Abstract : One of the most common cellular responses to DNA breakage is the covalent post-translational modification of the nuclear proteins with poly ADP ribose from the NAD+ as a precursor, which is mostly catalyzed by the poly-ADP-ribose polymerase1(PARP1).

Keywords : NAD+, PARP, ADPr, Post Translational Modification, DNA base editing, DNA damage signaling, ARTs.

One of the most common cellular responses to DNA breakage is the covalent post-translational modification of the nuclear proteins with poly ADP ribose from the NAD+ as a precursor, which is mostly catalyzed by the poly-ADP-ribose polymerase1(PARP1).

Keywords : NAD+, PARP, ADPr, Post Translational Modification, DNA base editing, DNA damage signaling, ARTs.

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