Publication Date: 2020/05/30
Abstract: One of the most common cellular responses to DNA breakage is the covalent post-translational modification of the nuclear proteins with poly ADP ribose from the NAD+ as a precursor, which is mostly catalyzed by the poly-ADP-ribose polymerase1(PARP1).
Keywords: NAD+, PARP, ADPr, Post Translational Modification, DNA base editing, DNA damage signaling, ARTs.
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT20MAY326.pdf
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