The Multifaceted Effects of Lactobacillus acidophilus on Endocrine, Gastrointestinal and Cardiovascular Health: A Clinical Study

Lana Lekić1

1

Publication Date: 2024/12/16

Abstract: Lactobacillus acidophilus is a probiotic bacterium widely recognized for its beneficial effects on gut health and systemic physiological functions. This study aimed to evaluate the impact of L. acidophilus (1.0 x 109 CFU, administered for one month) on endocrine, gastrointestinal, and cardiovascular parameters in 20 participants. The results demonstrated significant improvements across multiple systems. In the endocrine system, a slight reduction in TSH and cortisol levels and a significant decrease in insulin levels were observed, suggesting improved hormonal balance and insulin sensitivity. Gastrointestinal parameters, including transit time and subjective symptom assessment, showed marked improvement, with a reduction in transit time and alleviation of symptoms such as bloating and abdominal discomfort. Cardiovascular parameters also improved significantly, with reductions in systolic and diastolic blood pressure, LDL cholesterol, and triglycerides, indicating a better lipid profile and reduced cardiovascular risk. These findings highlight the potential of Lactobacillus acidophilus as a multifunctional probiotic capable of supporting metabolic, gastrointestinal, and cardiovascular health. The results underscore the need for further research on larger populations and longer treatment periods to validate these findings and explore underlying mechanisms.

Keywords: Lactobacillus Acidophillus, Endocrine Parameters, Gastrointestinal Parameters, Cardiovascular Parameters, Participants.

DOI: https://doi.org/10.5281/zenodo.14500380

PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT24DEC109.pdf

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