Post-Operative Application of Lidocaine with Epinephrine Effectively Mitigates Pain in Women who had Caesarean Section

Olubunmi Damilola Babatola; Afolabi M. Owojuyigbe; Odunayo Daniel Babatola; Busuyi Kolade Akinola; Olumide Akadiri1

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Publication Date: 2023/12/11

Abstract: The number of Caesarean sections performed worldwide is increasing as well as the cost of postoperative treatment. The management of pain post caesarean section is an important aspect of post- operative care which has contributed to high cost of maternal care and may contribute to maternal mortality especially in resource poor settings. This study assessed the safety and effectiveness of surgical site infiltration with lidocaine-epinephrine solution as post caesarean analgesia compared with non-infiltration. It was a prospective randomized controlled clinical trial. One hundred and forty (140) eligible pregnant women scheduled for elective caesarean section at term in University of Medical Sciences Teaching Hospital Complex (UNIMEDTHC) were randomly assigned to the study and control group, each with 70 participants. Surgical sites of the study group patients were infiltrated with 20mls of 2% lidocaine solution (400mg lidocaine+100μg epinephrine) stat while the control group patients were not. Both groups received the same adjuncts analgesic agents whereas rescue analgesics were given only after complaints of moderate to severe pain. The rescue analgesic consumption in the first 24 hours postoperatively was less in the study group compared to the control (120mg; 480mg). The mean time to onset of breastfeeding was significantly early (u =3.567, p < 0.001) in the study group compared to the control group. This study showed that surgical site infiltration with 2% lidocaine+epinephrine solution following caesarean section is safe, reduces pain scores and hence use of rescue analgesics postoperatively, it also increases the time of onset of breastfeeding thereby decreasing patient hospital stay.

Keywords: Caesarean Section, Postoperative Pain, Lidocaine, Epinephrine, Anesthesia.

DOI: https://doi.org/10.5281/zenodo.10437557

PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23NOV1619.pdf

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