One Pot and Three Component Synthesis of 4-aryl-3- Methylisoxazole-5(4H)-One Derivative in the Presence of Sodium Hypophosphite

Amit P.Tayade, Ramkrushna P. Pawar, Rajiv V. Khobare, Chandakant B.Mane, Nitin P. Tayde1

1

Publication Date: 2019/12/03

Abstract: sodium hypophosphite is also an effective catalyst use for one pot three component reaction contain ethyl acetoacetate react with hydroxylamine hydrochloride and various aromatic aldehyde, gives iso-oxazole. This reaction carried out in water at 800 C temperature . The product obtained with high yield in convenient time up to 1-2 hours.

Keywords: MCR, Aldehyde , Ethyl Acetoacetate , Hydroxylamine Hydrochloride , Sodium Hypophosphite, Green.

DOI: No DOI Available

PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT19NOV385.pdf

REFERENCES

No References Available