Insight of Epigenetics in Autoimmunity and Allergies

Aqsa Yahya; Iqra Yahya; Samreen Rana; Samia Dastgeer; Muqaddas Rana; Sadia Tabassum; Laraib Ali1

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Publication Date: 2023/04/13

Abstract: Epigenetic processes include DNA methylation, chromatin changes, and micro RNA-based signaling all play a role in controlling genome activity. Epigenetic regulation is present in practically every component of immunity, whether for host defense or in the form of interference resistance. These cycles are crucial in mediating dynamic reactions to the environment over the life span of an individual, although we are only beginning to grasp how dysregulation in these pathways may play a role in autoimmune disorders. The epigenetic mechanisms that affect immune development and, by extension, an individual's health and the course of disease, are covered in a clear and succinct manner here.

Keywords: Autoimmune Diseases, Epigenetics, DNA Methylation, Histone Modification, and mRNA.

DOI: https://doi.org/10.5281/zenodo.7825016

PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23MAR1957.pdf

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