Publication Date: 2024/02/03
Abstract: These issues can be successfully avoided with injectable hydrogels by releasing medication locally at the tumor site. The benefits of local toxicity on the tumor have prompted studies into whether hydrogels are appropriate for drug delivery. Different hydrogel drug delivery systems, such as heat-, pH-, light-, and dual- sensitive hydrogels, have been developed in accordance with different cancer types and stages. Recent developments in hydrogels and other drug delivery technologies are highlighted in this review. In conclusion, as we learn more about injectable hydrogels for cancer treatment at a site, their efficacy and durability as treatments improve. Promising avenues for future research include smart delivery systems that react differently to stimuli at different times based on alterations in the tumor site's microenvironment. Because there are numerous polymer systems to choose from that have diverse chemical properties and excellent performance,there has been an increase in interest in Injectable hydrogels have been used in cancer therapy in recent years.To address the shortcomings of the available treatments, several research teamsare developing ablation systems appropriate for thermal and photothermal ablation, radiation therapy, and chemotherapyThe initial polymers' structure and properties are frequently categorized by origin or syntheticity—are the main topics of our work, which reviews and discusses the most recent developments in injectable hydrogel technology.
Keywords: Polyphosphazenes (PPZ), Camptotechin (CPT), Tumor Cell Lysates 3 (TLR3), Nanocapsule-Based Hydrogels (NBL), Blood-Brain Barrier (BBB), Doxorubicin (DOX).
DOI: https://doi.org/10.5281/zenodo.10613097
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT24JAN976.pdf
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