Publication Date: 2023/06/13
Abstract: Manipulating fungi to enhance the yield of industrially important products is a fairly common practice and methods to do so are increasingly improving to maximize the yield of the product more than the presently used methods. Fungi form competent hosts for such manipulations and procedures because of their smaller genome sizes that can be studied and exploited for various research and industrial endeavors. This technique is commonly known to improve the regulation of lipid metabolism, production of fermentation products, heterologous proteins and genome evolutionary editing in Saccharomyces cerevisiae, Aspergillus sp., Rhizopus sp., Mucor sp. and Mortierella alpina.
Keywords: gene editing techniques; CRISPR/Cas9; Aspergillus oryzae; Aspergillus niger; Saccharomyces cerevisiae; Ogataea thermomethanolica; Rhizopus arrhizus; Mucor circinelloides; Mortierella alpina; heterologous protein production; lipid metabolism; fermentation products; evolutionary engineering; transformation.
DOI: https://doi.org/10.5281/zenodo.8031806
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23MAY2596.pdf
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