Publication Date: 2023/12/29
Abstract: Background/Aims. Percutaneous endoscopic gastrostomy (PEG) is frequently indicated in patients with global developmental delay (GDD) with dysphagia. The present study aims at evaluating the influence of PEG on the GER and the gastric emptying of liquids in children with GDD. Methods. 16 children with GDD (6M/10F, median age 9 yrs [1 - 17]) with clinically indicated PEG were evaluated with intraluminal impedance and pH monitoring and 13 C- acetate breath test (gastric emptying). Baseline and 5- month values for esophageal acid exposure, bolus contact time, number of reflux episodes and the gastric emptying half- time were compared with paired t-test. Results. The number of total reflux episodes raised after PEG (mean 18.8, 95% CI 1 to 36.3, P = 0.038), mainly due to an increase in weakly acid reflux episodes (mean difference 16.7, 95% CI 6.5 - 27, P = 0.004). The variation of the gastric emptying half- time was not significant at five months (+7.9 min (95% CI -9.9 to 25.7), P = 0.348). Conclusions. PEG placement did not affect the reflux index, the bolus contact time, and the gastric emptying. A slight increase in weakly acid reflux episodes without clinical repercussion was observed.
Keywords: Gastric Emptying; Breath Test; Cerebral Palsy; Gastrostomy;
DOI: https://doi.org/10.5281/zenodo.10441937
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23DEC1317.pdf
REFERENCES