Publication Date: 2019/09/07
Abstract: Aim To evaluate the levels of serum albumin in healthy subjects, gingivitis and periodontitis patients and their correlation. Materials and Methods This study was conducted upon 60 subjects of both gender with age range of 25-50 years and the inclusion with exclusion criterias were considered. Three groups were made with almost equal division of patients approximately 20 patients each in the group ; Clinically healthy subjects, gingivitis and periodontitis patients. At baseline dental examinations were carried out with Bleeding on probing, Probing depth, Gingival index, Loss of clinical attachment were measured. By Albumin estimation kit – Bromocresol green method (BCG) the Serum albumin concentration was measured. Results The levels of mean serum albumin among healthy, gingivitis and periodontitis group was 4.03 ± 0.35, 4.09 ± 0.20, 3.72 ± 0.14 respectively. Three groups were compared for mean serum albumin levels using Kruskal Wallis test and results were found statistically significant (p<0.001). The mean serum albumin levels in subjects among groups with Gingival index 0-1, 1.1-2 and 2.1-3 was 4.07±0.32, 4.04±0.29, 3.80±0.22 respectively. The difference of the mean serum albumin level among different gingival index score was found to be statistically significant (p<0.05). The mean serum levels in subjects with loss of attachment less than 5 mm was 3.76 ± 0.12 and in subjects with attachment loss more than or equal to 5 mm was 3.68 ± 0.15. The comparison was done using Mann-Whitney U test and the differences in the mean serum albumin level was not significantly different( p>0.05) . Conclusion Serum albumin concentration and the study groups had found an inverse association in this clinical trial. Also there was a finding that serum albumin level is reducing with an increase in gingival index and in loss of attachment.
Keywords: Gingivitis , Periodontitis, Serum Albumin.
DOI: No DOI Available
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT19JUL242.pdf
REFERENCES