Publication Date: 2023/04/14
Abstract: Background Kidney cancer in adults has a high metastatic potential with poor survival rates. Pronostic factors would improve the choice of a therapeutic method. We decided to revisit epidemiology and evaluate survival factors in kidney metastatic carcinomas in a Moroccan setting. Method: Retrospective data collect from 2017 to 2020 of all adults patients presenting with metastatic kidney carcinomas. Epidemiology and survival rates were analysed using SPSS. Results: We included 79 patients, predominantly over 60yo and male. Metastases were observed in lungs (73.4%), lymph nodes (39.2%), livers (31.6%), bones (35.4%) and peritoneum (17.8%). Metastases were concurrent to the primitive tumor in 59.5%. Histology was predominantly clear cell renal carcinoma. According to IMDC score, 77% of patients had an intermediate score. Global survival was 29%, better for patients with an intermediate score (p=0.009) as well as progression free survival (p=0.001). In multivariate analysis, only the OMS performance status (p=0.008) and height (0.02) were associated with survival. Conclusion Thé IMDC score is a suitable tool to classify patients with metastatic kidney cancers, in order to guide therapeutic choices.
Keywords: Epidemiology, Kidney, Cancer, Metastatic, Survival, Morocco.
DOI: https://doi.org/10.5281/zenodo.7828343
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23APR442.pdf
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