Publication Date: 2023/11/30
Abstract: Nanoparticle coating have great potential in biochemistry and medical science. It can provide biocompatibility, prolonged blood circulation and possibly resolve the drug resistance cancer problem. This article delves into the intricate realm of protein corona formation on nanoparticles, nanoscale metal-organic frameworks (nMOFs) as drug delivery systems, and the challenges associated with nanomedicine. It explores the impact of preparation techniques on the precision and interpretation of biomolecular/protein corona, shedding light on methods, causes of methodological problems, and typical misunderstandings. Additionally, the article investigates the potential of genetically engineered biomimetic nanoparticles for altering intracellular localization and enhancing payload delivery. It discusses the importance of accurate characterization, stability, and controlled release of nanoparticles for effective drug delivery. Furthermore, it explores antibacterial coatings, silver nanoparticle coatings, and coatings made of magnetic nanoparticles, offering insights into their applications and biocompatibility. This holistic examination underscores the critical need for methodological precision in nanomedicine, with implications for diagnostics, therapeutics, and future research endeavor’s.
Keywords: Nanoscale metal organic framework, protein corona, magnetic nanoparticles, antibacterial coating, silver nanoparticle coating, drug delivery.
DOI: https://doi.org/10.5281/zenodo.10224242
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23NOV581.pdf
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