Eco-Friendly One Pot Synthesis of Coumarin Derivatives by Pechmann Condensation using Tamarind Juice as a Biocatalyst

Dinesh N. Navale; Prasanna B. Ranade; Santosh W. Zote; Dnyaneshwar K. Kulal; Swapnil J. Wagh1

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Publication Date: 2023/03/10

Abstract: An efficient and eco-friendly synthetic method has been established for synthesis of 7-hydroxy-4-methyl coumarin and its derivatives using tamarind juice as a biocatalyst. The condensation reaction of Substituted phenol with ethyl acetoacetate (EAA) successfully carried out using tamarind juice as a green and efficient catalyst at 90°C in aqueous condition. This green biocatalyst has been utilised effectively for pechmann reaction with good yield of product, easy workup and eco-friendly reaction conditions.

Keywords: Pechmann Reaction, Tamarind Juice, Resorcinol, Ethyl Acetoacetate, Green Synthesis.

DOI: https://doi.org/10.5281/zenodo.7716411

PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23FEB1313.pdf

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