Publication Date: 2024/02/21
Abstract: Vitiligo is an autoimmune disorder or inflammatory condition associated with itchy, scaly skin & disfiguring skin lesion. Numerous studies on natural products with anti-psoriatic action have been conducted as a result of the lack of treatment options and accompanying drawbacks in allopathic therapy. Nigella sativa (Black cumin), Ocimum sanctum (Tulsileaves), GlycyrrhizaGlabra (Liquorice), Curcuma longa (Turmericrhizomes) was found to be efficacious and cheap anti-inflammatory and immuno modulator drugs with least in comparison to synthetic medications used to cure vitiligo, negative effects. These medications were chosen for the current investigation since the objective was to produce a herbal cream for use in vitiligo skin repigmentation therapy. A polyherbal cream design and development attempt was produced taking into account the aforementioned justification. Different crude drugs extracts were taken &polyherbal cream was prepared. Accelerated stability testing of three sample has been conducted in the environmental chamber with temperature 25 ± 100C and humidity 60 ± 10% RH. The “F1” formulation were found to be stable with no sign of phase separation and no change in the colour. The sensitivity test patch has also been used, and there has been no indication of skin irritability or allergy symptoms.
Keywords: Vitiligo, Polyherbal Cream, Synthetic chemical, Cosmeceutical, Repigmentation
DOI: https://doi.org/10.5281/zenodo.10686866
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT24FEB721.pdf
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