Publication Date: 2024/01/04
Abstract: The plant is primarily used to make colchicine, which is used therapeutically to cure gout and in experiments with cellular chromosomes. In cases of familial Mediterranean fever, hepatic cirrhosis, primary biliary cirrhosis, and chronic progressive multiple sclerosis, it is utilised as adjuvant therapy. Examples of skin problems include primary amyloidosis, Behçet illness, pseudo-gout, psoriasis, Palmo-plantar pustulosis, and Dermatitis Herpetiformis. Aims and Objective- The purpose of this study and summary of the literature on homoeopathic medicine's use of colchicum and colchicine. Methodology – Relevant books and research articles have been extracted from different databases, including as PubMed, Google Scholar, Cochrane Library, Science direct, Theme-E-Journal of homoeopathy. Search terms were ‘Colchicum & Homoeopathy, Colchicine, Pharmacology and colchicum, Action of Colchicine, Inflammation and colchicum, Alternative system of medicine, Toxicity of colchicine, Various homoeopathic materia medica books were searched and the data of colchicum Autumnale in inflammation and gout was mentioned. Conclusion- This narrative review concludes that homoeopathic medicine colchicum Autumnale is effective in muscular skeletal system likes gout, joint pain, fibrous tissues etc, it continues to be a preferred medication for the management of acute gouty arthritis. It works well to treat inflammation brought on by crystals. It needs to be specified in Joint inflammatory diseases. No fatal toxicity was observed. Requirement of dose is less in colchicum Autumnale than colchicine. Overdoses on colchicine are quite uncommon. but have high mortality requiring rapid treatment.
Keywords: Homoeopathy, Colchicum, Colchicine, Inflammation, Mechanism of Action, Pharmacokinetics , Toxicity.
DOI: https://doi.org/10.5281/zenodo.10458460
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23DEC1726.pdf
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