Publication Date: 2023/09/07
Abstract: Background: Locally advanced breast cancer encompasses a heterogeneous collection of breast neoplasms, constituting approximately 10 to 20% of newly diagnosed breast cancer cases annually. The patient often presents with an ulcerative lesion in the breast with foul-smelling or bloody discharge associated with supra clavicular lymphadenopathy and axillary lymphadenopathy. Case report: In this study, we reported a case of a 48-year-old female with complaints of an ulcerated lesion with severe pain over the right breast and foul-smelling serosanguinous discharge from the ulcer. Later, it was diagnosed as a case of carcinoma of the right breast stage cT4bN1Mx. The patient was given neoadjuvant chemotherapy and three sessions of hyperthermia per week for 22 sessions. Results: The tumor responded well to neoadjuvant chemotherapy and hyperthermia, converting the inoperable tumor into an operable tumor. Conclusion: Combined neoadjuvant chemotherapy and hyperthermia significantly reduce the size of locally advanced breast cancer by converting it into an operable one, and there was a reduction in pain over the ulcer, improving the patient's quality of life.
Keywords: Breast Cancer, Chemosensitizer, Chemotherapy, Hyperthermia, Neoplasm.
DOI: https://doi.org/10.5281/zenodo.8323396
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23AUG1100.pdf
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