Publication Date: 2022/12/24
Abstract: Alcoholism is a general behavioral disorder with excessive intake of alcohol; it results the dependency of alcohol with aversive symptoms upon alcohol withdrawal. Withdrawal from chronic ethanol exposure causes anxiety like symptoms, like: vomiting, nausea, mental confusion, tremors, excessive sweating, ataxia, increased heart rate and convulsion like symptoms. Ethanol withdrawal has been postulated to be associated with specific molecular mechanisms and neuroadaptive changes that may lead to an increased and persistent anxiety state. In this study, investigate the effect of 6- Shogaol in ethanol-dependent mice using Fluoxetine as a control. Measures made in this model were consistent with literature data it suggested that the ethanol dosing daily basis ranging
Keywords: Alcoholism, alcohol withdrawal syndrome, anxiety, Depression, Social interaction test, elevated plus maze test, light and dark paradigm, mice.
DOI: https://doi.org/10.5281/zenodo.7478781
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT22NOV907_(1).pdf
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