Publication Date: 2023/08/05
Abstract: A series of few 3-(benzylideneamino) -2,7- dimethyl-benzo[4,5]thieno[2,3-d]pyrimidine-4-one were prepared in laboratory. They were purified by manual column chromatography as well as re-crystallized from various solvents. Their structures were characterized by spectroscopy techniques such as Proton-NMR and Carbon-NMR. Their masses were detected by using Mass-spectrometry. They were screened for their therapeutic and pharmacological activities as a biological function. Some of the novel target compounds were found to have strong biological activities with respect to Itraconozole and Furacin standard drugs.
Keywords: 3-(benzylideneamino)- 2,7-dimethylbenzo[4,5] thieno-[2,3-d]pyrimidine-4-one, Antifungal activity, Antimicrobial activity, Minimal Inhibition Concentration.
DOI: https://doi.org/10.5281/zenodo.8217244
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23JUN1563.pdf
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