Publication Date: 2024/02/03
Abstract: Plants have long been utilized to treat a variety of illnesses. Search for male antifertility factor of medicinal plants remained a potential area of investigation. The present investigation was aimed to study the effect of oral administration of two medicinal plants , Melia azedarach (leaf) and Momordica dioica(fruit) at a dose of 100mg/kg body weight for 21 days on reproductive organs of male albino rats. Body weight, Reproductive Organ weight , Fructose content in Coagulating gland(CG), Acid phosphatase activity in Ventral prostate(VP), Total protein in Seminal vesicle(SV) were investigated in both control and treated groups. Histology of testis in treated rats showed degenerative changes in the seminiferous tubules. The decrease in sperm count with wider lumen, organ weight, fructose content in CG, protein content in SV, suggesting the antifertility activity in both tested plants. Corpus luteal sites, Implantation sites, and Litter size were also found significantly reduced.
Keywords: Antifertility, Biochemical Parameters, Melia Azedarach, Momordicadioica, Sperm Count, Testis.
DOI: https://doi.org/10.5281/zenodo.10613167
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT24JAN1361.pdf
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