Publication Date: 2023/09/02
Abstract: The Global concern regarding new multidrug resistant pathogenic microbial strains developing due to increased usage and misuse of antibiotics has paved the way for reviving an alternate plant based safe and effective medicine which targets pathogens without rendering them drug resistant. Plants which are a crucial part of our daily diet tend to possess potent antimicrobial compounds, it is therefore imperative to screen these plants for their antimicrobial activity, thus providing an alternate readily available source of medicine to combat the various pathogenic microbial infectious agents. The present study was carried out to evaluate the antimicrobial activity of plant extracts that we use in day to day lives. The antimicrobial potential of two different plant extracts were screened against six pathogenic microorganisms. The methanolic, ethanolic extracts of Aloe vera and Mentha piperita were subjected to a test of the antimicrobial properties by agar well diffusion method. The results indicated that the extracts of Mentha piperita exhibited potent antimicrobial properties. The highest antimicrobial activity was observed in the methanolic extract of Mentha piperita against Bacillus subtilis followed by ethanolic extract against Bacillus subtilis. Standard drugs were used for comparing the inhibitory action of plant extracts against commercially available antibiotics such as Gentamicin, Penicillin-G and Chloramphenicol against the bacteria. The organic solvents such as n-hexane was also used for testing the antimicrobial activity. The leaf extracts showed moderate to high activity against both Gram positive and Gram negative bacteria. When the antimicrobial properties of both the plants were compared the extract of Mentha piperita showed higher antimicrobial properties than Aloe vera. This shows that the Mentha piperita possesses effective compounds which are responsible for eliminating the pathogenic bacteria, and the antimicrobial activity was due to the presence of various bioactive compounds such as the alkaloids, flavonoids, steroids and phenolic compounds present in the organic extracts.
Keywords: No Keywords Available
DOI: https://doi.org/10.5281/zenodo.8311190
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23JUN1991.pdf
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