Publication Date: 2023/06/16
Abstract: The design of the oral drug delivery system, which is still the dominant method of drug delivery despite a number of drawbacks, must take into account the ease of administration and increased patient compliance. Due to the insufficient development of the muscular and neurological systems in children, as well as cases of elderly individuals with Parkinson's disease or hand tremors, fast-dissolving tablets have become one of the most well-liked and widely recognised dose forms. Today's solid dosage forms, such as capsules and tablets, are dealing with issues like dysphagia, which leads to numerous instances. In mouth dissolving tablets superdisintegrants are incorporated in right amount for quick disintegration with improved bioavailability.FDTs either disintegrate or dissolve rapidly in saliva without the need for water. Real fast-dissolving tablets are made to dissolve in saliva incredibly quicklyin less than 60 seconds. By using different processes, such as direct compression, tablet moulding, freeze drying, and spray drying nanonization, one can create a drug delivery system that dissolves quickly.This article provides a brief description of FDTs, including their definition, benefits, uses, key characteristics, drawbacks, problems in their development, Technology used for manufacturing of fast dissolving tablets, Common excipients used in fast dissolving tablets and commercially available fastdissolving tablet formulations.
Keywords: Oral drug delivery, Fast dissolving tablet, Superdisintegrants, Bioavailability, Technology.
DOI: https://doi.org/10.5281/zenodo.8047479
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23JUN097.pdf
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