Publication Date: 2023/07/21
Abstract: The majority of men who develop penile cancer are in their sixth decade of life. The most common histology is squamous cell carcinoma (SCC), and about half of the cases are thought to be influenced by human papillomavirus (HPV) infection. Few therapeutic choices are available to patients with serious illnesses, and their prognosis is still grim. Risk factors for PSCC (HPV) include phimosis, chronic inflammation, poor penile hygiene, smoking, immunosuppression, and circumcision in children. Accurate and early surgical staging of the inguinal lymph nodes is crucial for disease management due to the early lymphatic dissemination that separates PSCC from other malignancies and the limitations of imaging to detect micrometastatic sickness. Localized and advanced penile cancers, as well as their treatment, have a major impact on patients' and survivors' quality of life since they impair sexual and urinary function and produce lymphoedema. Rare cancer known as PSCC has been given the orphan disease designation.
Keywords: Penile cancer, Human papillomavirus (HPV), Squamous cell carcinoma (SSC)
DOI: https://doi.org/10.5281/zenodo.8170795
PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23JUL411.pdf
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