A Case Report on Faropenem Induced Focal Seizures

Zuha Shariff; Dr. T. Vithya; Dr. Shankar Prasad1

1

Publication Date: 2023/08/21

Abstract: Faropenem, an orally active Carbapenem, showcases a distinctive molecular structure characterized by a beta-lactam ring accompanied by a chiral tetrahydrofuran substitution at the C2 position. This structural modification serves a dual purpose: it enhances the compound's chemical stability while also diminishing the potential for adverse effects within the central nervous system (CNS) [1]. Consequently, Faropenem emerges as a notably safer therapeutic choice in comparison to other compounds within its pharmacological class. However, it is essential to highlight that the current body of literature remains notably lacking in substantial evidence linking Faropenem usage to triggering of seizures. In light of this, we present a case report featuring a 48-year-old woman who, subsequent to receiving the Faropenem antibiotic, presented with a series of recurrent focal seizures.

Keywords: Adverse Drug Reaction; Carbapenem; Faropenem; Seizure.

DOI: https://doi.org/10.5281/zenodo.8269088

PDF: https://ijirst.demo4.arinfotech.co/assets/upload/files/IJISRT23AUG996.pdf

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